Ontology highlight
ABSTRACT:
SUBMITTER: Liu M
PROVIDER: S-EPMC5460036 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Liu Mengmeng M Li Qian Q Liang Le L Li Jiang J Wang Kun K Li Jiajun J Lv Min M Chen Nan N Song Haiyun H Lee Joon J Shi Jiye J Wang Lihua L Lal Ratnesh R Fan Chunhai C
Nature communications 20170531
Mechanistic understanding of the endocytosis and intracellular trafficking of nanoparticles is essential for designing smart theranostic carriers. Physico-chemical properties, including size, clustering and surface chemistry of nanoparticles regulate their cellular uptake and transport. Significantly, even single nanoparticles could cluster intracellularly, yet their clustering state and subsequent trafficking are not well understood. Here, we used DNA-decorated gold (fPlas-gold) nanoparticles a ...[more]