Ontology highlight
ABSTRACT:
SUBMITTER: Bianchini G
PROVIDER: S-EPMC5461122 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Bianchini Giampaolo G Balko Justin M JM Mayer Ingrid A IA Sanders Melinda E ME Gianni Luca L
Nature reviews. Clinical oncology 20160517 11
Chemotherapy is the primary established systemic treatment for patients with triple-negative breast cancer (TNBC) in both the early and advanced-stages of the disease. The lack of targeted therapies and the poor prognosis of patients with TNBC have fostered a major effort to discover actionable molecular targets to treat patients with these tumours. Massively parallel sequencing and other 'omics' technologies have revealed an unexpected level of heterogeneity of TNBCs and have led to the identif ...[more]