Ontology highlight
ABSTRACT:
SUBMITTER: Dickinson AM
PROVIDER: S-EPMC5461268 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Dickinson Anne M AM Norden Jean J Li Shuang S Hromadnikova Ilona I Schmid Christoph C Schmetzer Helga H Jochem-Kolb Hans H
Frontiers in immunology 20170607
The success of hematopoietic stem cell transplantation (HSCT) lies with the ability of the engrafting immune system to remove residual leukemia cells <i>via</i> a graft-versus-leukemia effect (GvL), caused either spontaneously post-HSCT or <i>via</i> donor lymphocyte infusion. GvL effects can also be initiated by allogenic mismatched natural killer cells, antigen-specific T cells, and activated dendritic cells of leukemic origin. The history and further application of this GvL effect and the mai ...[more]