Skin Sodium Concentration Correlates with Left Ventricular Hypertrophy in CKD.

ABSTRACT: The pathogenesis of left ventricular hypertrophy in patients with CKD is incompletely understood. Sodium intake, which is usually assessed by measuring urinary sodium excretion, has been inconsistently linked with left ventricular hypertrophy. However, tissues such as skin and muscle may store sodium. Using ²³sodium-magnetic resonance imaging, a technique recently developed for the assessment of tissue sodium content in humans, we determined skin sodium content at the level of the calf in 99 patients with mild to moderate CKD (42 women; median [range] age, 65 [23-78] years). We also assessed total body overhydration (bioimpedance spectroscopy), 24-hour BP, and left ventricular mass (cardiac magnetic resonance imaging). Skin sodium content, but not total body overhydration, corre

SUBMITTER: Schneider MP 

PROVIDER: S-EPMC5461788 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature