Ontology highlight
ABSTRACT:
SUBMITTER: Rauniyar N
PROVIDER: S-EPMC5462478 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Rauniyar Navin N Peng Gang G Lam TuKiet T TT Zhao Hongyu H Mor Gil G Williams Kenneth R KR
Biomarker insights 20170605
A data-independent acquisition (DIA)/parallel reaction monitoring (PRM) workflow was implemented to identify improved ovarian cancer biomarkers. Data-independent acquisition on ovarian cancer versus control sera and literature searches identified 50 biomarkers and indicated that apolipoprotein A-IV (ApoA-IV) is the most significantly differentially regulated protein. Parallel reaction monitoring with Targeted Ovarian Cancer Proteome Assay validated differential ApoA-IV expression and quantified ...[more]