Ontology highlight
ABSTRACT:
SUBMITTER: Mvumbi DM
PROVIDER: S-EPMC5464640 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Mvumbi Dieudonné Makaba DM Bobanga Thierry Lengu TL Kayembe Jean-Marie Ntumba JN Mvumbi Georges Lelo GL Situakibanza Hippolyte Nani-Tuma HN Benoit-Vical Françoise F Melin Pierrette P De Mol Patrick P Hayette Marie-Pierre MP
PloS one 20170608 6
Malaria is a major public health problem in the Democratic Republic of Congo. Despite progress achieved over the past decade in the fight against malaria, further efforts have to be done such as in the surveillance and the containment of Plasmodium falciparum resistant strains. We investigated resistance to artemisinin-based combination therapies currently in use in Democratic Republic of Congo by surveying molecular polymorphisms in three genes: pfcrt, pfmdr1 and pfk13 to explore possible emerg ...[more]