Ontology highlight
ABSTRACT:
SUBMITTER: Sala Torra O
PROVIDER: S-EPMC5465962 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20170103 4
We used next-generation sequencing (NGS) of the immunoglobulin genes to evaluate residual disease in 153 specimens from 32 patients with adult B cell acute lymphoblastic leukemia enrolled in a single multicenter study. The sequencing results were compared with multiparameter flow cytometry (MFC) data in 66 specimens (25 patients) analyzed by both methods. There was a strong concordance (82%) between the methods in the qualitative determination of the presence of disease. However, in 17% of cases ...[more]