Detection and partial characterization of simian immunodeficiency virus SIVsm strains from bush meat samples from rural Sierra Leone.
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ABSTRACT:
SUBMITTER: Apetrei C
PROVIDER: S-EPMC546599 | biostudies-literature | 2005 Feb
REPOSITORIES: biostudies-literature
Publications
Detection and partial characterization of simian immunodeficiency virus SIVsm strains from bush meat samples from rural Sierra Leone.
Apetrei Cristian C Metzger Michael J MJ Richardson David D Ling Binhua B Telfer Paul T PT Reed Patricia P Robertson David L DL Marx Preston A PA
Journal of virology 20050201 4
Human immunodeficiency virus type 2 (HIV-2) originated from simian immunodeficiency viruses (SIVs) that naturally infect sooty mangabeys (SMs; Cercocebus atys). In order to further investigate the relationship between HIV-2 and SIVsm, the SIV specific to the SM, we characterized seven new SIVsm strains from SMs sold in Sierra Leone markets as bush meat. The gag, pol, and env sequences showed that, while the viruses of all seven SMs belonged to the SIVsm-HIV-2 lineage, they were highly divergent ...[more]
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