Ontology highlight
ABSTRACT:
SUBMITTER: Shevlin M
PROVIDER: S-EPMC5467193 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
ACS medicinal chemistry letters 20170517 6
Large arrays of hypothesis-driven, rationally designed experiments are powerful tools for solving complex chemical problems. Conceptual and practical aspects of chemical high-throughput experimentation are discussed. A case study in the application of high-throughput experimentation to a key synthetic step in a drug discovery program and subsequent optimization for the first large scale synthesis of a drug candidate is exemplified. ...[more]