Evidence of Mitochondrial Dysfunction in Autism: Biochemical Links, Genetic-Based Associations, and Non-Energy-Related Mechanisms.
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SUBMITTER: Griffiths KK
PROVIDER: S-EPMC5467355 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
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Evidence of Mitochondrial Dysfunction in Autism: Biochemical Links, Genetic-Based Associations, and Non-Energy-Related Mechanisms.
Griffiths Keren K KK Levy Richard J RJ
Oxidative medicine and cellular longevity 20170529
Autism spectrum disorder (ASD), the fastest growing developmental disability in the United States, represents a group of neurodevelopmental disorders characterized by impaired social interaction and communication as well as restricted and repetitive behavior. The underlying cause of autism is unknown and therapy is currently limited to targeting behavioral abnormalities. Emerging studies suggest a link between mitochondrial dysfunction and ASD. Here, we review the evidence demonstrating this pot ...[more]
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