Ontology highlight
ABSTRACT: Implications for practice
Currently, there is uncertainity on the role of surgery in MRCC and on the choice of available guidelines in relapsed RCC. The best practice is individualization of targeted therapies. Systematic review of guidelines can help to identify unmet medical needs and areas of future research.
SUBMITTER: Bamias A
PROVIDER: S-EPMC5469586 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Bamias Aristotle A Escudier Bernard B Sternberg Cora N CN Zagouri Flora F Dellis Athanasios A Djavan Bob B Tzannis Kimon K Kontovinis Loukas L Stravodimos Konstantinos K Papatsoris Athanasios A Mitropoulos Dionysios D Deliveliotis Charalampos C Dimopoulos Meletios-Athanasios MA Constantinides Constantine A CA
The oncologist 20170607 6
The landscape of local and systemic therapy of renal cell carcinoma (RCC) is rapidly changing. The increase in the incidental finding of small renal tumors has increased the application of nephron-sparing procedures, while ten novel agents targeting the vascular endothelial growth factor (VEGF) or the mammalian target of rapamycin pathways, or inhibiting the interaction of the programmed death 1 receptor with its ligand, have been approved since 2006 and have dramatically improved the prognosis ...[more]