Unknown

Dataset Information

0

Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost.


ABSTRACT: Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.Please see related Research article: http://dx.doi.org/10.1186/s13059-014-0565-1 and Please see response from Lovell et al: https://www.dx.doi.org/10.1186/s13059-017-1234-y.

SUBMITTER: Bornelov S 

PROVIDER: S-EPMC5470226 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature

altmetric image

Publications

Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost.

Bornelöv Susanne S   Seroussi Eyal E   Yosefi Sara S   Pendavis Ken K   Burgess Shane C SC   Grabherr Manfred M   Friedman-Einat Miriam M   Andersson Leif L  

Genome biology 20170614 1


Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes.Please see related Research article: http://dx.doi.org/10.1186/s13059-014-0565-1 and Please see r  ...[more]

Similar Datasets

| S-EPMC4696596 | biostudies-literature
| S-EPMC7068835 | biostudies-literature
| S-EPMC7193864 | biostudies-literature
| S-EPMC7328319 | biostudies-literature
2014-02-01 | E-TABM-1186 | biostudies-arrayexpress
2013-01-16 | E-MEXP-3071 | biostudies-arrayexpress
| S-EPMC7427385 | biostudies-literature
| S-EPMC7427396 | biostudies-literature