Ion Elevators and Escalators in Multilevel Structures for Lossless Ion Manipulations.

ABSTRACT: We describe two approaches based upon ion "elevator" and "escalator" components that allow moving ions to different levels in structures for lossless ion manipulations (SLIM). Guided by ion motion simulations, we designed elevator and escalator components based upon ion current measurements providing essentially lossless transmission in multilevel designs. The ion elevator design allowed ions to efficiently bridge a 4 mm gap between levels. The component was integrated in a SLIM and coupled to a QTOF mass spectrometer using an ion funnel interface to evaluate the m/z range transmitted as compared to transmission within a level (e.g., in a linear section). The analysis of singly charged ions of m/z 600-2700 produced similar mass spectra for both elevator and straight (linear motion) compone

SUBMITTER: Ibrahim YM 

PROVIDER: S-EPMC5470846 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature