Ontology highlight
ABSTRACT:
SUBMITTER: Testani JM
PROVIDER: S-EPMC5471359 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Testani Jeffrey M JM Hanberg Jennifer S JS Arroyo Juan Pablo JP Brisco Meredith A MA Ter Maaten Jozine M JM Wilson F Perry FP Bellumkonda Lavanya L Jacoby Daniel D Tang W H Wilson WH Parikh Chirag R CR
European journal of heart failure 20160113 6
<h4>Aims</h4>Hyponatraemia is strongly associated with adverse outcomes in heart failure. However, accumulating evidence suggests that chloride may play an important role in renal salt sensing and regulation of neurohormonal and sodium-conserving pathways. Our objective was to determine the prognostic importance of hypochloraemia in patients with heart failure.<h4>Methods and results</h4>Patients in the BEST trial with baseline serum chloride values were evaluated (n = 2699). Hypochloraemia was ...[more]