Ontology highlight
ABSTRACT:
SUBMITTER: Ocque AJ
PROVIDER: S-EPMC5472061 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Ocque Andrew J AJ Hagler Colleen E CE DiFrancesco Robin R Morse Gene D GD Talal Andrew H AH
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20170324
An ultra-performance liquid chromatography with triple quadrupole mass spectrometry method was developed and validated for the determination of direct acting antiviral drug concentrations in human liver fine needle aspirates. Liver fine needle aspirate (FNA) biopsy samples were homogenized in acetonitrile to stabilize the analytes and precipitate protein. The acetonitrile supernatants were diluted with internal standards and mobile phase. Separation was achieved with a Waters Acquity BEH C18 col ...[more]