Ontology highlight
ABSTRACT:
SUBMITTER: Zala D
PROVIDER: S-EPMC5473427 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Zala Diana D Schlattner Uwe U Desvignes Thomas T Bobe Julien J Roux Aurélien A Chavrier Philippe P Boissan Mathieu M
F1000Research 20170518
Nucleoside triphosphate (NTP)s, like ATP (adenosine 5'-triphosphate) and GTP (guanosine 5'-triphosphate), have long been considered sufficiently concentrated and diffusible to fuel all cellular ATPases (adenosine triphosphatases) and GTPases (guanosine triphosphatases) in an energetically healthy cell without becoming limiting for function. However, increasing evidence for the importance of local ATP and GTP pools, synthesised in close proximity to ATP- or GTP-consuming reactions, has fundamenta ...[more]