Ontology highlight
ABSTRACT:
SUBMITTER: Walker-Sperling VE
PROVIDER: S-EPMC5474502 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Walker-Sperling Victoria E VE Pohlmeyer Christopher W CW Veenhuis Rebecca T RT May Megan M Luna Krystle A KA Kirkpatrick Allison R AR Laeyendecker Oliver O Cox Andrea L AL Carrington Mary M Bailey Justin R JR Arduino Roberto C RC Blankson Joel N JN
EBioMedicine 20170126
HIV-1 controllers are patients who control HIV-1 viral replication without antiretroviral therapy. Control is achieved very early in the course of infection, but the mechanisms through which viral replication is restricted are not fully understood. We describe a patient who presented with acute HIV-1 infection and was found to have an HIV-1 RNA level of <100copies/mL. She did not have any known protective HLA alleles, but significant immune activation of CD8+ T cells and natural killer (NK) cell ...[more]