Methods of MicroRNA Promoter Prediction and Transcription Factor Mediated Regulatory Network.
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ABSTRACT:
SUBMITTER: Zhao Y
PROVIDER: S-EPMC5474535 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Methods of MicroRNA Promoter Prediction and Transcription Factor Mediated Regulatory Network.
Zhao Yuming Y Wang Fang F Chen Su S Wan Jun J Wang Guohua G
BioMed research international 20170605
MicroRNAs (miRNAs) are short (~22 nucleotides) noncoding RNAs and disseminated throughout the genome, either in the intergenic regions or in the intronic sequences of protein-coding genes. MiRNAs have been proved to play important roles in regulating gene expression. Hence, understanding the transcriptional mechanism of miRNA genes is a very critical step to uncover the whole regulatory network. A number of miRNA promoter prediction models have been proposed in the past decade. This review summa ...[more]
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