Ontology highlight
ABSTRACT:
SUBMITTER: McCarthy RL
PROVIDER: S-EPMC5476666 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
McCarthy Ryan L RL Mak Duncan H DH Burks Jared K JK Barton Michelle C MC
Scientific reports 20170619 1
Mass cytometry presents an exceptional opportunity to interrogate the biology of highly heterogeneous cell populations, owing to the ability to collect highly parametric proteomic data at a single cell level. However, sample-to-sample variability, due to antibody staining and/or instrument sensitivity, can introduce substantial artifacts into the data, which can in turn lead to erroneous conclusions. This variability can be eliminated by sample barcoding which enables samples to be pooled, stain ...[more]