Ontology highlight
ABSTRACT:
SUBMITTER: Almaani S
PROVIDER: S-EPMC5477208 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Almaani Salem S Meara Alexa A Rovin Brad H BH
Clinical journal of the American Society of Nephrology : CJASN 20161107 5
SLE is a chronic inflammatory disease that affects the kidneys in about 50% of patients. Lupus nephritis is a major risk factor for overall morbidity and mortality in SLE, and despite potent anti-inflammatory and immunosuppressive therapies still ends in CKD or ESRD for too many patients. This review highlights recent updates in our understanding of disease epidemiology, genetics, pathogenesis, and treatment in an effort to establish a framework for lupus nephritis management that is patient-spe ...[more]