Effect of Metabolic Syndrome on the Mobility Benefit of a Structured Physical Activity Intervention-The Lifestyle Interventions and Independence for Elders Randomized Clinical Trial.

ABSTRACT:

Objectives

To test whether structured physical activity (PA) is associated with a greater reduction in major mobility disability (MMD) in older persons with metabolic syndrome (MetS) than in those without.

Design

Data from the Lifestyle Interventions and Independence for Elders (LIFE) Study, a multicenter randomized trial of 1,635 persons with assessments every 6 months (average 2.7 years).

Setting

Eight U.S. centers.

Participants

Sedentary men and women aged 70 to 89 with functional limitations (N = 1,535); 100 participants were excluded because of missing MetS data.

Intervention

Participants were randomized to a moderate-intensity PA program (n = 766) or a health education program (n = 769).

Measurements

MetS was defined according to the 2009 mu

SUBMITTER: Botoseneanu A 

PROVIDER: S-EPMC5478451 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature