Ontology highlight
ABSTRACT:
SUBMITTER: Eldridge BN
PROVIDER: S-EPMC5479712 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Eldridge Brittany N BN Xing Fei F Fahrenholtz Cale D CD Singh Ravi N RN
Toxicology in vitro : an international journal published in association with BIBRA 20170309
There is a growing interest in the use of multiwalled carbon nanotubes (MWCNTs) to treat diseases of the brain. Little is known about the effects of MWCNTs on human brain microvascular endothelial cells (HBMECs), which make up the blood vessels in the brain. In our studies, we evaluate the cytotoxicity of MWCNTs and acid oxidized MWNCTs, with or without a phospholipid-polyethylene glycol coating. We determined the cytotoxic effects of MWCNTs on both tissue-mimicking cultures of HBMECs grown on b ...[more]