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Ongoing haemolytic uraemic syndrome (HUS) outbreak caused by sorbitol-fermenting (SF) Shiga toxin-producing Escherichia coli (STEC) O157, Germany, December 2016 to May 2017.


ABSTRACT: We report an ongoing, protracted and geographically dispersed outbreak of haemolytic uraemic syndrome (HUS) and gastroenteritis in Germany, involving 30 cases since December 2016. The outbreak was caused by the sorbitol-fermenting immotile variant of Shiga toxin-producing (STEC) Escherichia coli O157. Molecular typing revealed close relatedness between isolates from 14 cases. One HUS patient died. Results of a case-control study suggest packaged minced meat as the most likely food vehicle. Food safety investigations are ongoing.

SUBMITTER: Vygen-Bonnet S 

PROVIDER: S-EPMC5479985 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature

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Ongoing haemolytic uraemic syndrome (HUS) outbreak caused by sorbitol-fermenting (SF) Shiga toxin-producing Escherichia coli (STEC) O157, Germany, December 2016 to May 2017.

Vygen-Bonnet Sabine S   Rosner Bettina B   Wilking Hendrik H   Fruth Angelika A   Prager Rita R   Kossow Annelene A   Lang Christina C   Simon Sandra S   Seidel Juliane J   Faber Mirko M   Schielke Anika A   Michaelis Kai K   Holzer Alexandra A   Kamphausen Rolf R   Kalhöfer Daniela D   Thole Sebastian S   Mellmann Alexander A   Flieger Antje A   Stark Klaus K  

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20170501 21


We report an ongoing, protracted and geographically dispersed outbreak of haemolytic uraemic syndrome (HUS) and gastroenteritis in Germany, involving 30 cases since December 2016. The outbreak was caused by the sorbitol-fermenting immotile variant of Shiga toxin-producing (STEC) Escherichia coli O157. Molecular typing revealed close relatedness between isolates from 14 cases. One HUS patient died. Results of a case-control study suggest packaged minced meat as the most likely food vehicle. Food  ...[more]

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