Ontology highlight
ABSTRACT:
SUBMITTER: Grossman LI
PROVIDER: S-EPMC5480048 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Grossman Lawrence I LI Purandare Neeraja N Arshad Rooshan R Gladyck Stephanie S Somayajulu Mallika M Hüttemann Maik M Aras Siddhesh S
Oxidative medicine and cellular longevity 20170608
The central role of energy metabolism in cellular activities is becoming widely recognized. However, there are many gaps in our knowledge of the mechanisms by which mitochondria evaluate their status and call upon the nucleus to make adjustments. Recently, a protein family consisting of twin CX<sub>9</sub>C proteins has been shown to play a role in human pathophysiology. We focus here on two family members, the isoforms CHCHD2 (renamed MNRR1) and CHCHD10. The better studied isoform, MNRR1, has t ...[more]