Ontology highlight
ABSTRACT:
SUBMITTER: Liu C
PROVIDER: S-EPMC5480051 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Liu Can C Zhou Nan N Li Jieying J Kong Jun J Guan Xi X Wang Xudong X
Disease markers 20170608
Eg5 (kinesin spindle protein) plays an essential role in mitosis. Inhibition of Eg5 function results in cell cycle arrest at mitosis, which leads to cell death. To date, Eg5 expression and its prognostic significance have not been studied in hepatocellular carcinoma (HCC). In this study, 26 freshly frozen HCC tissue samples and matched peritumoral tissue samples were evaluated with a one-step qPCR test and immunohistochemical (IHC) analysis was conducted on 156 HCC samples to investigate the rel ...[more]