Total synthesis of brevenal.
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ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC5484051 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Publications
Total synthesis of brevenal.
Zhang Yuan Y Rohanna John J Zhou Jie J Iyer Karthik K Rainier Jon D JD
Journal of the American Chemical Society 20110215 9
This Article describes the total synthesis of the marine ladder toxin brevenal utilizing a convergent synthetic strategy. Critical to the success of this work was the use of olefinic-ester cyclization reactions and the utilization of glycal epoxides as precursors to C-C and C-H bonds. ...[more]
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