Cerebral cholesterol granuloma in homozygous familial hypercholesterolemia.
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ABSTRACT:
SUBMITTER: Francis GA
PROVIDER: S-EPMC548411 | biostudies-literature | 2005 Feb
REPOSITORIES: biostudies-literature
Publications
Cerebral cholesterol granuloma in homozygous familial hypercholesterolemia.
Francis Gordon A GA Johnson Royce L RL Findlay J Max JM Wang Jian J Hegele Robert A RA
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050201 4
Familial hypercholesterolemia (FH) is characterized by the accumulation of excess cholesterol in tissues including the artery wall and tendons. We describe a patient with homozygous FH who presented with asymptomatic cholesterol granuloma of the brain. The patient's plasma low-density lipoprotein cholesterol level was remarkably responsive to combination hypolipidemic therapy with statin plus ezetimibe. This case illustrates another potential complication of whole-body cholesterol excess and und ...[more]
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