Unknown

Dataset Information

0

Sequential change detection and monitoring of temporal trends in random-effects meta-analysis.


ABSTRACT: Temporal changes in magnitude of effect sizes reported in many areas of research are a threat to the credibility of the results and conclusions of meta-analysis. Numerous sequential methods for meta-analysis have been proposed to detect changes and monitor trends in effect sizes so that meta-analysis can be updated when necessary and interpreted based on the time it was conducted. The difficulties of sequential meta-analysis under the random-effects model are caused by dependencies in increments introduced by the estimation of the heterogeneity parameter ?2 . In this paper, we propose the use of a retrospective cumulative sum (CUSUM)-type test with bootstrap critical values. This method allows retrospective analysis of the past trajectory of cumulative effects in random-effects meta-analysis and its visualization on a chart similar to CUSUM chart. Simulation results show that the new method demonstrates good control of Type I error regardless of the number or size of the studies and the amount of heterogeneity. Application of the new method is illustrated on two examples of medical meta-analyses. © 2016 The Authors. Research Synthesis Methods published by John Wiley & Sons Ltd.

SUBMITTER: Dogo SH 

PROVIDER: S-EPMC5484389 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature

altmetric image

Publications

Sequential change detection and monitoring of temporal trends in random-effects meta-analysis.

Dogo Samson Henry SH   Clark Allan A   Kulinskaya Elena E  

Research synthesis methods 20161208 2


Temporal changes in magnitude of effect sizes reported in many areas of research are a threat to the credibility of the results and conclusions of meta-analysis. Numerous sequential methods for meta-analysis have been proposed to detect changes and monitor trends in effect sizes so that meta-analysis can be updated when necessary and interpreted based on the time it was conducted. The difficulties of sequential meta-analysis under the random-effects model are caused by dependencies in increments  ...[more]

Similar Datasets

| S-EPMC4681410 | biostudies-literature
| S-EPMC5590730 | biostudies-literature
| S-EPMC8052775 | biostudies-literature
| S-EPMC5517826 | biostudies-other
| S-EPMC3494021 | biostudies-literature
| S-EPMC4305202 | biostudies-literature
| S-EPMC4489045 | biostudies-literature
| S-EPMC6455044 | biostudies-literature
| S-EPMC8361666 | biostudies-literature
| S-EPMC2787531 | biostudies-literature