State of Art of Cancer Pharmacogenomics in Latin American Populations.
Ontology highlight
ABSTRACT:
SUBMITTER: Lopez-Cortes A
PROVIDER: S-EPMC5485925 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Publications
State of Art of Cancer Pharmacogenomics in Latin American Populations.
López-Cortés Andrés A Guerrero Santiago S Redal María Ana MA Alvarado Angel Tito AT Quiñones Luis Abel LA
International journal of molecular sciences 20170523 6
Over the past decades, several studies have shown that tumor-related somatic and germline alterations predicts tumor prognosis, drug response and toxicity. Latin American populations present a vast geno-phenotypic diversity due to the great interethnic and interracial mixing. This genetic flow leads to the appearance of complex characteristics that allow individuals to adapt to endemic environments, such as high altitude or extreme tropical weather. These genetic changes, most of them subtle and ...[more]
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