Ontology highlight
ABSTRACT:
SUBMITTER: Kindler JM
PROVIDER: S-EPMC5489353 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Kindler Joseph M JM Pollock Norman K NK Laing Emma M EM Oshri Assaf A Jenkins Nathan T NT Isales Carlos M CM Hamrick Mark W MW Ding Ke-Hong KH Hausman Dorothy B DB McCabe George P GP Martin Berdine R BR Hill Gallant Kathleen M KM Warden Stuart J SJ Weaver Connie M CM Peacock Munro M Lewis Richard D RD
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20170701 7
IGF-I is a pivotal hormone in pediatric musculoskeletal development. Although recent data suggest that the role of IGF-I in total body lean mass and total body bone mass accrual may be compromised in children with insulin resistance, cortical bone geometric outcomes have not been studied in this context. Therefore, we explored the influence of insulin resistance on the relationship between IGF-I and cortical bone in children. A secondary aim was to examine the influence of insulin resistance on ...[more]