Ontology highlight
ABSTRACT:
SUBMITTER: Rahme M
PROVIDER: S-EPMC5489368 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Rahme Maya M Sharara Sima Lynn SL Baddoura Rafic R Habib Robert H RH Halaby Georges G Arabi Asma A Singh Ravinder J RJ Kassem Moustapha M Mahfoud Ziyad Z Hoteit Maha M Daher Rose T RT Bassil Darina D El Ferkh Karim K El-Hajj Fuleihan Ghada G
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20170518 7
The optimal dose of vitamin D to optimize bone metabolism in the elderly is unclear. We tested the hypothesis that vitamin D, at a dose higher than recommended by the Institute of Medicine (IOM), has a beneficial effect on bone remodeling and mass. In this double-blind trial we randomized 257 overweight elderly subjects to receive 1000 mg of elemental calcium citrate/day, and the daily equivalent of 3750 IU/day or 600 IU/day of vitamin D3 for 1 year. The subjects' mean age was 71 ± 4 years, body ...[more]