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Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.

ABSTRACT: A large number of cDNA inserts were sequenced from a high-quality library of chicken bursal lymphocyte cDNAs. Comparisons to public gene databases indicate that the cDNA collection represents more than 2,000 new, full-length transcripts. This resource defines the structure and the coding potential of a large fraction of B-cell specific and housekeeping genes whose function can be analyzed by disruption in the chicken DT40 B-cell line.

SUBMITTER: Caldwell RB

PROVIDER: S-EPMC549067 | biostudies-literature | 2005

REPOSITORIES: biostudies-literature

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Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.

Caldwell Randolph B RB Kierzek Andrzej M AM Arakawa Hiroshi H Bezzubov Yuri Y Zaim Jolanta J Fiedler Petra P Kutter Stefan S Blagodatski Artem A Kostovska Diyana D Koter Marek M Plachy Jiri J Carninci Piero P Hayashizaki Yoshihide Y Buerstedde Jean-Marie JM

Genome biology 20041223 1

A large number of cDNA inserts were sequenced from a high-quality library of chicken bursal lymphocyte cDNAs. Comparisons to public gene databases indicate that the cDNA collection represents more than 2,000 new, full-length transcripts. This resource defines the structure and the coding potential of a large fraction of B-cell specific and housekeeping genes whose function can be analyzed by disruption in the chicken DT40 B-cell line. ...[more]

PMID: 15642098

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