Ontology highlight
ABSTRACT:
SUBMITTER: Hillier D
PROVIDER: S-EPMC5490790 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Hillier Daniel D Fiscella Michele M Drinnenberg Antonia A Trenholm Stuart S Rompani Santiago B SB Raics Zoltan Z Katona Gergely G Juettner Josephine J Hierlemann Andreas A Rozsa Balazs B Roska Botond B
Nature neuroscience 20170522 7
How neuronal computations in the sensory periphery contribute to computations in the cortex is not well understood. We examined this question in the context of visual-motion processing in the retina and primary visual cortex (V1) of mice. We disrupted retinal direction selectivity, either exclusively along the horizontal axis using FRMD7 mutants or along all directions by ablating starburst amacrine cells, and monitored neuronal activity in layer 2/3 of V1 during stimulation with visual motion. ...[more]