Ontology highlight
ABSTRACT:
SUBMITTER: Kroesen VM
PROVIDER: S-EPMC5492311 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Frontiers in immunology 20170630
Lengthy, antimicrobial therapy targeting the pathogen is the mainstay of conventional tuberculosis treatment, complicated by emerging drug resistances. Host-directed therapies, including non-steroidal anti-inflammatory drugs (NSAIDs), in contrast, target host factors to mitigate disease severity. In the present Systematic Review, we investigate whether NSAIDs display any effects as therapy of TB and discuss possible mechanisms of action of NSAIDs as adjunctive therapy of TB. Ten studies, seven p ...[more]