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Inducible metronidazole resistance and nim genes in clinical Bacteroides fragilis group isolates.


ABSTRACT: Nitroimidazole resistance (nim) genes were detected in 2% of 1,502 clinical Bacteroides fragilis group strains isolated from 19 European countries, and a novel nim gene was identified. High metronidazole resistance could be induced in nim-positive strains, which emphasizes the importance of acknowledging metronidazole resistance in the clinical setting.

SUBMITTER: Lofmark S 

PROVIDER: S-EPMC549250 | biostudies-literature | 2005 Mar

REPOSITORIES: biostudies-literature

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Inducible metronidazole resistance and nim genes in clinical Bacteroides fragilis group isolates.

Löfmark Sonja S   Fang Hong H   Hedberg Maria M   Edlund Charlotta C  

Antimicrobial agents and chemotherapy 20050301 3


Nitroimidazole resistance (nim) genes were detected in 2% of 1,502 clinical Bacteroides fragilis group strains isolated from 19 European countries, and a novel nim gene was identified. High metronidazole resistance could be induced in nim-positive strains, which emphasizes the importance of acknowledging metronidazole resistance in the clinical setting. ...[more]

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