Ontology highlight
ABSTRACT:
SUBMITTER: Barton DL
PROVIDER: S-EPMC5493290 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Barton Daniel L DL Henkes Silke S Weijer Cornelis J CJ Sknepnek Rastko R
PLoS computational biology 20170630 6
We introduce an Active Vertex Model (AVM) for cell-resolution studies of the mechanics of confluent epithelial tissues consisting of tens of thousands of cells, with a level of detail inaccessible to similar methods. The AVM combines the Vertex Model for confluent epithelial tissues with active matter dynamics. This introduces a natural description of the cell motion and accounts for motion patterns observed on multiple scales. Furthermore, cell contacts are generated dynamically from positions ...[more]