Ontology highlight
ABSTRACT:
SUBMITTER: Gannoun-Zaki L
PROVIDER: S-EPMC549332 | biostudies-literature | 2005 Feb
REPOSITORIES: biostudies-literature
Gannoun-Zaki Laïla L Jost Amy A Mu Jianbing J Deitsch Kirk W KW Wellems Thomas E TE
Eukaryotic cell 20050201 2
Introns of Plasmodium falciparum var genes act as transcriptional silencing elements that help control antigenic variations. In transfected episomes, intron silencing of a drug-selectable marker under var promoter control is reversed by the spontaneous deletion of key intron regions. The resulting promoter activation does not affect the transcription of chromosomal var genes. ...[more]