Ontology highlight
ABSTRACT:
SUBMITTER: Jokerst JV
PROVIDER: S-EPMC5493650 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Jokerst Jesse V JV Cauwenberghs Nicholas N Kuznetsova Tatiana T Haddad Francois F Sweeney Timothy T Hou Jiayi J Rosenberg-Hasson Yael Y Zhao Eric E Schutt Robert R Bolli Roberto R Traverse Jay H JH Pepine Carl J CJ Henry Timothy D TD Schulman Ivonne H IH Moyé Lem L Taylor Doris A DA Yang Phillip C PC
Scientific reports 20170630 1
Bone marrow mononuclear cell (BM-MNC) therapy in ST-elevation acute myocardial infarction (STEMI) has no biological inclusion criteria. Here, we analyzed 63 biomarkers and cytokines in baseline plasma samples from 77 STEMI patients treated with BM-MNCs in the TIME and Late-TIME trials as well as 61 STEMI patients treated with placebo. Response to cell therapy was defined by changes in left ventricular ejection fraction, systolic/diastolic volumes, and wall motion indexes. We investigated the cli ...[more]