Ontology highlight
ABSTRACT:
SUBMITTER: Freeman NS
PROVIDER: S-EPMC5493935 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
The Journal of organic chemistry 20160517 11
Nucleodyes, visibly colored chromophoric nucleoside analogues, are reported. Design criteria are outlined and the syntheses of cytidine and uridine azo dye analogues derived from 6-aminouracil are described. Structural analysis shows that the nucleodyes are sound structural analogues of their native nucleoside counterparts, and photophysical studies demonstrate that the nucleodyes are sensitive to microenvironmental changes. Quantum chemical calculations are presented as a valuable complementary ...[more]