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Preclinical Studies and Translational Applications of Intracerebral Hemorrhage.

ABSTRACT: Intracerebral hemorrhage (ICH) which refers to bleeding in the brain is a very deleterious condition with high mortality and disability rate. Surgery or conservative therapy remains the treatment option. Various studies have divided the disease process of ICH into primary and secondary injury, for which knowledge into these processes has yielded many preclinical and clinical treatment options. The aim of this review is to highlight some of the new experimental drugs as well as other treatment options like stem cell therapy, rehabilitation, and nanomedicine and mention some translational clinical applications that have been done with these treatment options.

SUBMITTER: Siaw-Debrah F

PROVIDER: S-EPMC5494071 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Preclinical Studies and Translational Applications of Intracerebral Hemorrhage.

Siaw-Debrah Felix F Nyanzu Mark M Ni Haoqi H Lin Xiao X Xu Zhu Z Ruan Linhui L Zhuge Qichuan Q Huang Lijie L

BioMed research international 20170618

Intracerebral hemorrhage (ICH) which refers to bleeding in the brain is a very deleterious condition with high mortality and disability rate. Surgery or conservative therapy remains the treatment option. Various studies have divided the disease process of ICH into primary and secondary injury, for which knowledge into these processes has yielded many preclinical and clinical treatment options. The aim of this review is to highlight some of the new experimental drugs as well as other treatment op ...[more]

PMID: 28698874

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