Ontology highlight
ABSTRACT:
SUBMITTER: Matter N
PROVIDER: S-EPMC549580 | biostudies-literature | 2005 Feb
REPOSITORIES: biostudies-literature
Matter Nathalie N König Harald H
Nucleic acids research 20050224 4
The existence of two sophisticated parallel splicing machineries in multicellular organisms has raised intriguing questions--ranging from their impact on proteome expansion to the evolution of splicing and of metazoan genomes. Exploring roles for the distinct splicing systems in vivo has, however, been restricted by the lack of techniques to selectively inhibit their function in cells. In this study, we show that morpholino oligomers complementary to the branch-site recognition elements of U2 or ...[more]