Ontology highlight
ABSTRACT:
SUBMITTER: Pescio LG
PROVIDER: S-EPMC5496039 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Pescio Lucila Gisele LG Santacreu Bruno Jaime BJ Lopez Vanina Gisela VG Paván Carlos Humberto CH Romero Daniela Judith DJ Favale Nicolás Octavio NO Sterin-Speziale Norma Beatriz NB
Journal of lipid research 20170517 7
Ceramides (Cers) and complex sphingolipids with defined acyl chain lengths play important roles in numerous cell processes. Six Cer synthase (CerS) isoenzymes (CerS1-6) are the key enzymes responsible for the production of the diversity of molecular species. In this study, we investigated the changes in sphingolipid metabolism during the differentiation of Madin-Darby canine kidney (MDCK) cells. By MALDI TOF TOF MS, we analyzed the molecular species of Cer, glucosylceramide (GlcCer), lactosylcer ...[more]