Ontology highlight
ABSTRACT:
SUBMITTER: Hoseini SS
PROVIDER: S-EPMC5496242 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Hoseini Sayed Shahabuddin SS Cheung Nai-Kong V NV
Cancer letters 20170417
Hepatocellular carcinoma (HCC) is one of the most lethal cancers worldwide with an overall survival rate of less than 15% in developed countries. Despite attempts at new therapeutic strategies, the majority of patients succumb to this cancer. Buttressed by the highly successful clinical impact in melanoma, immunotherapy is gaining momentum as the next treatment modality for many human cancers. Chimeric antigen receptors (CAR) contain the antigen binding moieties of a monoclonal antibody and the ...[more]