Ontology highlight
ABSTRACT:
SUBMITTER: Kim MJ
PROVIDER: S-EPMC5498141 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Kim Myung-Jin MJ Park Seon Young SY Chang Hae Ryung HR Jung Eun Young EY Munkhjargal Anudari A Lim Jong-Seok JS Lee Myeong-Sok MS Kim Yonghwan Y
BMB reports 20170601 6
Bone morphogenetic protein type 2 receptor (BMPR2) is one of the transforming growth factor-β (TGF-β) superfamily receptors, performing diverse roles during embryonic development, vasculogenesis, and osteogenesis. Human BMPR2 consists of 1,038 amino acids, and contains functionally conserved extracellular, transmembrane, kinase, and C-terminal cytoplasmic domains. Bone morphogenetic proteins (BMPs) engage the tetrameric complex, composed of BMPR2 and its corresponding type 1 receptors, which ini ...[more]