Ontology highlight
ABSTRACT:
SUBMITTER: Hofmann SR
PROVIDER: S-EPMC5500598 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Molecular and cellular pediatrics 20170706 1
Chronic non-bacterial osteomyelitis (CNO) belongs to the growing spectrum of autoinflammatory diseases and primarily affects the skeletal system. Peak onset ranges between 7 and 12 years of age. The clinical spectrum of CNO covers sometimes asymptomatic inflammation of single bones at the one end and chronically active or recurrent multifocal osteitis at the other.Despite the intense scientific efforts, the exact molecular mechanisms of CNO remain unknown. Recent data suggest CNO as a geneticall ...[more]