Ontology highlight
ABSTRACT:
SUBMITTER: Takahashi JS
PROVIDER: S-EPMC5501165 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Nature reviews. Genetics 20161219 3
Circadian clocks are endogenous oscillators that control 24-hour physiological and behavioural processes in organisms. These cell-autonomous clocks are composed of a transcription-translation-based autoregulatory feedback loop. With the development of next-generation sequencing approaches, biochemical and genomic insights into circadian function have recently come into focus. Genome-wide analyses of the clock transcriptional feedback loop have revealed a global circadian regulation of processes ...[more]