Ontology highlight
ABSTRACT:
SUBMITTER: Christiansen MK
PROVIDER: S-EPMC5501546 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Christiansen Morten Krogh MK Larsen Sanne Bøjet SB Nyegaard Mette M Neergaard-Petersen Søs S Ajjan Ramzi R Würtz Morten M Grove Erik Lerkevang EL Hvas Anne-Mette AM Jensen Henrik Kjærulf HK Kristensen Steen Dalby SD
PloS one 20170707 7
<h4>Introduction</h4>Genetic constitution and inflammation both contribute to development of coronary artery disease (CAD). Several CAD-associated single-nucleotide polymorphisms (SNPs) have recently been identified, but their functions are largely unknown. We investigated the associations between CAD-associated SNPs and five CAD-related inflammatory biomarkers.<h4>Methods</h4>We genotyped 45 CAD-associated SNPs in 701 stable CAD patients in whom levels of high-sensitivity C-reactive protein (hs ...[more]