Ontology highlight
ABSTRACT:
SUBMITTER: Landoulsi Z
PROVIDER: S-EPMC5501550 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Landoulsi Zied Z Benromdhan Sawssan S Ben Djebara Mouna M Damak Mariem M Dallali Hamza H Kefi Rym R Abdelhak Sonia S Gargouri-Berrechid Amina A Mhiri Chokri C Gouider Riadh R
BMC medical genetics 20170706 1
<h4>Background</h4>In North African populations, G2019S mutation in LRRK2 gene, encoding for the leucine-rich repeat kinase 2, is the most prevalent mutation linked to familial and sporadic Parkinson's disease (PD). Early detection of G2019S by fast genetic testing is very important to guide PD's diagnosis and support patients and their family caregivers for better management of their life according to disease's evolution.<h4>Methods</h4>In our study, a genetic PD's diagnosis tool was developed ...[more]