Self-Organization of Spatial Patterning in Human Embryonic Stem Cells.
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ABSTRACT:
SUBMITTER: Deglincerti A
PROVIDER: S-EPMC5502691 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Self-Organization of Spatial Patterning in Human Embryonic Stem Cells.
Deglincerti Alessia A Etoc Fred F Ozair M Zeeshan MZ Brivanlou Ali H AH
Current topics in developmental biology 20160202
The developing embryo is a remarkable example of self-organization, where functional units are created in a complex spatiotemporal choreography. Recently, human embryonic stem cells (ESCs) have been used to recapitulate in vitro the self-organization programs that are executed in the embryo in vivo. This represents an unique opportunity to address self-organization in humans that is otherwise not addressable with current technologies. In this chapter, we review the recent literature on self-orga ...[more]
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