Ontology highlight
ABSTRACT:
SUBMITTER: Loomba R
PROVIDER: S-EPMC5502730 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Cell metabolism 20170501 5
The presence of advanced fibrosis in nonalcoholic fatty liver disease (NAFLD) is the most important predictor of liver mortality. There are limited data on the diagnostic accuracy of gut microbiota-derived signature for predicting the presence of advanced fibrosis. In this prospective study, we characterized the gut microbiome compositions using whole-genome shotgun sequencing of DNA extracted from stool samples. This study included 86 uniquely well-characterized patients with biopsy-proven NAFL ...[more]